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PROIN ER™

(phenylpropanolamine hydrochloride extended-release tablets)

couple laying down with dog on their lap

One tablet. Once a day. All day effectiveness.

Proin ER bottles
Proin ER bottles
Now your patients can get the same, effective treatment for urinary incontinence (UI) due to urethral sphincter hypotonus that you’ve come to trust from PROIN® in a convenient, once-a-day dose with PROIN ER™ (phenylpropanolamine hydrochloride extended-release tablets). Factor in its delicious flavoring, and it all adds up to improved compliance and happier dogs and families.
Proin ER bottles

How does PROIN ER™ work?

PROIN ER™ works by increasing urethral sphincter muscle tone to help prevent urinary leakage.
proin ER bottle with two dogs

Special offer

Buy 4 and get a FREE gift.

Contact your MWI Representative for more details.

Offer valid 3/1 – 4/30/2023

PROIN ER™ by the numbers

PROIN ER™ is an effective, easy-to-use treatment of UI due to urethral sphincter hypotonus in spayed, female dogs.
99%
of owners, when asked on Day 28, assessed their dog as "improved" or "stayed the same."¹
82.2%
of doses voluntarily consumed when given without or with a small amount of food.¹
1Pegasus Laboratories, Inc. (2019). Freedom of Information (FOI) Summary for PROIN ER (phenylpropanolamine hydrochloride extended-release tablets) Dogs: US, (NADA 141-517). Center for Veterinary Medicine (CVM).

The PROIN ER™ advantage

  • 1x per day - One extended-release tablet per day can be conveniently given with food.
  • Accurate dosing - Available in four weight-based strengths for accurate dosage of virtually any sized dog weighing 10 pounds or larger. See prescribing information for details.
  • Enticing flavor - Flavored tablets improve compliance and make treatment easy.
  • Steady absorption - Patented release technology provides controlled release that ensures steady absorption.
  • FDA approved - The only once-a-day, FDA-approved medication for the control of urinary incontinence due to urethral sphincter hypotonus in dogs.
  • Convenient packaging - 30ct. & 90ct. bottles are conveniently sized for storage and dosing.
IMPORTANT SAFETY INFORMATION:
For oral use in dogs only. Not for human use. Keep out of reach of children. If accidentally ingested by humans, contact a physician immediately. The most commonly reported side effects were vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, increased water consumption, weight loss, weakness, fever, panting, and reversible changes in skin color (flushing or bright pink). Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported. In some cases death, including euthanasia has been reported. Sudden death was sometimes preceded by vocalization or collapse. Instances of dogs chewing through closed vials of PROIN® and eating the vial contents have been reported, in some cases resulting in overdose. Keep the product in a secured storage area out of the reach of pets in order to prevent accidental ingestion or overdose, as dogs may willingly consume more than the recommended dosage of PROIN® Chewable Tablets or PROIN ER™ tablets. Contact your veterinarian immediately if the dog ingests more tablets than prescribed or if other pets ingest PROIN Chewable tablets or PROIN ER tablets. PROIN and PROIN ER may cause elevated blood pressure and should be used with caution in dogs with pre-existing heart disease, high blood pressure, liver disease, kidney insufficiency, diabetes, glaucoma, and other conditions associated with high blood pressure. Dogs may transition from PROIN Chewable Tablets to PROIN ER without a break in administration. However, do not alternate PROIN ER with PROIN Chewable Tablets because the effectiveness and safety of interchangeable use have not been evaluated. The safe use of PROIN and PROIN ER in dogs used for breeding purposes, during pregnancy or in lactating bitches, has not been evaluated. Contact your veterinarian if you notice restlessness or irritability, loss of appetite, the incontinence persists or worsens, or any other unusual signs. See prescribing information for complete details regarding adverse events, warning and precautions or visit prnpharmacal.com.

Treating UI just got easy-ER

The controlled release mechanism in our patented extended-release technology helps PROIN ER™ maintain steady absorption throughout the day. Plus, there’s no washout period when transitioning from PROIN to PROIN ER.
little girl with her dog taking in the view