
What is FerAppease®?

The active ingredient of FerAppease® is a synthetic analogue of the Maternal Bovine Appeasing Substance (MBAS). MBAS is naturally secreted by the sebaceous gland located on the skin of the mammary gland with the unique function of inducing an appeasing effect on the nursing offspring.
FerAppease® is topically applied and the active ingredient (MBAS) is assimilated by the vomeronasal gland located in the nose of the animals. The MBAS stimulation of the vomeronasal gland desensitizes regions of the amygdala and the hypothalamus, dramatically decreasing threat perception and its downstream stress consequences.

Threat perception

When should FerAppease® be used?
Stressful management events such as:
- Weaning
- Dehorning
- Castration
- Branding
- Transportation
Stressful physiological events such as:
- Parturition
- Interruption of lactation (dry off)
- Breeding
"We started using FerAppease® on our fresh heifers and we immediately noticed that treated animals were calmer and were much easier to load into the parlor, making it safer for the animals and the people."
Scott Blevins - Dairy Manager, Wiese Brothers, Greenleaf, WI

How is FerAppease® applied?

FerAppease® is for use only in healthy cattle by topical administration to the nuchal skin and the skin above the muzzle.
For adult animals: Apply 5ml of FerAppease® to the nuchal skin and a second 5ml application to the skin above the muzzle.
For youngstock: Apply 2.5ml of FerAppease® to the nuchal skin and a second 2.5ml application to the skin above the muzzle.
