Get to know Reconcile® (fluoxetine hydrochloride)


Reconcile®, a flavored, chewable tablet that contains fluoxetine hydrochloride, was developed specifically for dogs with separation anxiety and is available again from a trusted manufacturer.
Reconcile chewable tablets are FDA approved for the treatment of canine separation anxiety in conjunction with a behavior modification plan directed by a veterinarian and carried out by the pet’s owner.
A dog with separation anxiety is not a hopeless case. When it is clear that the behaviors are not caused by a physical problem, using a behavior treatment plan that includes medication can help the affected dog become less anxious and more relaxed in the owner’s absence.

How does Reconcile® work?
Neurotransmitters, such as serotonin, are released from the presynaptic neuron and attach to receptors on the postsynaptic site. They are then reabsorbed back into the presynaptic site.
Research has shown that control of anxiety is one function of serotonin. Reconcile, a selective serotonin reuptake inhibitor (SSRI), helps correct the imbalance by blocking the reuptake of serotonin and temporarily increasing the level in the synapse.
Mode of action

Behavioral conditions are the #1 reason for euthanasia and relinquishment
Efficacy data
How well does Reconcile® work?
Behavioral improvement after 1 week
42%
Reconcile + behavior modification
18%
Behavior modification alone
Behavioral improvement after 8 weeks
73%
Reconcile + behavior modification
51%
Behavior modification alone

Product highlights

- Once-a-day, flavored, chewable tablet — highly appealing and easy to administer
- FDA approved for use in dogs in conjunction with a behavior modification plan
- Affordable for veterinarians to stock and pet owners to purchase—priced considerably lower than when previously on the market
- Reduces stress for both pet and owner, strengthening the human-animal bond
- Veterinary - exclusive formulation
